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1

Mutations in PRDM5 in Brittle Cornea Syndrome Identify a Pathway Regulating Extracellular Matrix Development and Maintenance

Emma M.M. Burkitt Wright, Helen L. Spencer, Sarah B. Daly, Forbes D.C. Manson, Leo A.H. Zeef, Jill Urquhart, Nicoletta Zoppi, Richard Bonshek, Ioannis Tosounidis, Meyyammai Mohan, Colm Madden, Annabel

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

2

Expulsion of Trichuris muris is associated with increased expression of angiogenin 4 in the gut and increased acidity of mucins within the goblet cell

Riccardo D'Elia, Matthew L deSchoolmeester, Leo AH Zeef, Steven H Wright, Alan D Pemberton, Kathryn J Else

Journal:

Year:

2009

Language:

english

File:

PDF, 4.47 MB

english, 2009

3

Antibiotic resistance mechanisms of mutant EF-Tu species in Escherichia coli

Kraal, Barend, Zeef, Leo A. H., Mesters, Jeroen R., Boon, Kathy, Vorstenbosch, Erik L. H., Bosch, Leendert, Anborgh, Pieter H., Parmeggiani, Andrea, Hilgenfeld, Rolf

Journal:

Biochemistry and Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.56 MB

english, 1995

4

Regulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo

Deignan, Lisa, Pinheiro, Marco T., Sutcliffe, Catherine, Saunders, Abbie, Wilcockson, Scott G., Zeef, Leo A. H., Donaldson, Ian J., Ashe, Hilary L., Perrimon, Norbert

Journal:

Year:

2016

Language:

english

File:

PDF, 21.19 MB

english, 2016

5

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

Rodrigues-Pinto, Ricardo, Ward, Lizzy, Humphreys, Matthew, Zeef, Leo A. H., Berry, Andrew, Hanley, Karen Piper, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.20 MB

english, 2018

6

Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses

Shaw, Tovah N., Inkson, Colette A., Villegas-Mendez, Ana, Pattinson, David J., Strangward, Patrick, Else, Kathryn J., Draper, Simon J., Zeef, Leo A. H., Couper, Kevin N.

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 5.86 MB

english, 2019

7

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation

Ben M. Minogue, Stephen M. Richardson, Leo A. H. Zeef, Anthony J. Freemont, Judith A. Hoyland

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

8

Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(−/−) mice

Andrew Collett, Norman B. Higgs, Meritxell Gironella, Leo A.H. Zeef, Andy Hayes, Emil Salmo, Najib Haboubi, Juan L. Iovanna, Gordon L. Carlson, Geoffrey Warhurst

Journal:

Inflammatory Bowel Diseases

Year:

2008

Language:

english

File:

PDF, 369 KB

english, 2008

9

Colonic transcriptional profiling in resistance and susceptibility to trichuriasis: Phenotyping a chronic colitis and lessons for iatrogenic helminthosis

S.E. Levison, J.T. McLaughlin, L.A.H. Zeef, P. Fisher, R.K. Grencis, J.L. Pennock

Journal:

Inflammatory Bowel Diseases

Year:

2010

Language:

english

File:

PDF, 2.78 MB

english, 2010

10

Genome-wide analysis of gene expression duringXenopus tropicalistadpole tail regeneration

Nick R Love, Yaoyao Chen, Boyan Bonev, Michael J Gilchrist, Lynne Fairclough, Robert Lea, Timothy J Mohun, Roberto Paredes, Leo AH Zeef, Enrique Amaya

Journal:

BMC Developmental Biology

Year:

2011

Language:

english

File:

PDF, 1.16 MB

english, 2011

11

Stromal derived factor-1 exerts differential regulation on distinct cortical cell populationsin vitro

James Pritchett, Clare Wright, Leo Zeef, Bagirathy Nadarajah

Journal:

BMC Developmental Biology

Year:

2007

Language:

english

File:

PDF, 2.69 MB

english, 2007

12

Growth control of the eukaryote cell: a systems biology study in yeast

Juan I Castrillo, Leo A Zeef, David C Hoyle, Nianshu Zhang, Andrew Hayes, David CJ Gardner, Michael J Cornell, June Petty, Luke Hakes, Leanne Wardleworth, Bharat Rash, Marie Brown, Warwick B Dunn, Dav

Journal:

Journal of Biology

Year:

2007

Language:

english

File:

PDF, 719 KB

english, 2007

13

5α-Dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization

SC Gilliver, JPD Ruckshanthi, MJ Hardman, LAH Zeef, GS Ashcroft

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 739 KB

english, 2009

14

Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells

Carlo Vascotto, Laura Cesaratto, Leo A. H. Zeef, Marta Deganuto, Chiara D'Ambrosio, Andrea Scaloni, Milena Romanello, Giuseppe Damante, Giulio Taglialatela, Daniela Delneri, Mark R. Kelley, Sankar Mit

Journal:

Year:

2009

Language:

english

File:

PDF, 829 KB

english, 2009

15

A technique for targeted mutagenesis of the EF-Tu chromosomal gene by M13-mediated gene replacement

Leo A. H. Zeef, Leendert Bosch

Journal:

Molecular Genetics and Genomics

Year:

1993

Language:

english

File:

PDF, 948 KB

english, 1993

16

Gene expression profiling of ozone-treatedArabidopsis abi1tdinsertional mutant: protein phosphatase 2C ABI1 modulates biosynthesis ratio of ABA and ethylene

Agnieszka Ludwików, Dorota Kierzek, Patrick Gallois, Leo Zeef, Jan Sadowski

Journal:

Year:

2009

Language:

english

File:

PDF, 562 KB

english, 2009

17

Age-related differences in the timing of stimulus and response processes during visual selective attention: Performance and psychophysiological analyses

ELLY J. ZEEF, ALBERT KOK

Journal:

Psychophysiology

Year:

1993

File:

PDF, 5.05 MB

1993

18

Perceptual factors affecting age-related differences in focused attention: Performance and psychophysiological analyses

ELLY J. ZEEF, CORINE J. SONKE, ALBERT KOK, MEREL M. BUITEN, J. LEON KENEMANS

Journal:

Psychophysiology

Year:

1996

File:

PDF, 3.86 MB

1996

19

Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures

Delneri, Daniela, Hoyle, David C, Gkargkas, Konstantinos, Cross, Emma J M, Rash, Bharat, Zeef, Leo, Leong, Hui-Sun, Davey, Hazel M, Hayes, Andrew, Kell, Douglas B

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 380 KB

english, 2007

20

Transformation of the tropane alkaloid-producing medicinal plant Hyoscyamus muticus by particle bombardment

Leo A. H. Zeef, Paul Christou, Mark J. Leech

Journal:

Transgenic Research

Year:

2000

Language:

english

File:

PDF, 98 KB

english, 2000

21

Mutations in PRDM5 in Brittle Cornea Syndrome Identify a Pathway Regulating Extracellular Matrix Development and Maintenance

Emma M.M. Burkitt Wright, Helen L. Spencer, Sarah B. Daly, Forbes D.C. Manson, Leo A.H. Zeef, Jill Urquhart, Nicoletta Zoppi, Richard Bonshek, Ioannis Tosounidis, Meyyammai Mohan, Colm Madden, Annabel

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 36 KB

english, 2011

22

Thioredoxin interacting protein is increased in sensory neurons in experimental diabetes

Sally A. Price, Natalie J. Gardiner, Beatriz Duran-Jimenez, Leo A.H. Zeef, Irina G. Obrosova, David R. Tomlinson

Journal:

Year:

2006

Language:

english

File:

PDF, 842 KB

english, 2006

23

A growth-defective kirromycin-resistant EF-Tu Escherichia coli mutant and a spontaneously evolved suppression of the defect

Leo A.H. Zeef, Jeroen R. Mesters, Barend Kraal, Leendert Bosch

Journal:

Year:

1995

Language:

english

File:

PDF, 696 KB

english, 1995

24

Motor and non-motor behaviour in experimental Huntington's disease

Dagmar H. Zeef, Rinske Vlamings, Lee Wei Lim, Sonny Tan, Marcus L.F. Janssen, Ali Jahanshahi, Govert Hoogland, Jos Prickaerts, Harry W.M. Steinbusch, Yasin Temel

Journal:

Behavioural Brain Research

Year:

2012

Language:

english

File:

PDF, 539 KB

english, 2012

25

Memory deficits in the transgenic rat model of Huntington's disease

Dagmar H. Zeef, Nick P. van Goethem, Rinske Vlamings, Frédéric Schaper, Ali Jahanshahi, Sarah Hescham, Stephan von Hörsten, Jos Prickaerts, Yasin Temel

Journal:

Behavioural Brain Research

Year:

2012

Language:

english

File:

PDF, 297 KB

english, 2012

26

Notch protection against apoptosis in T-ALL cells mediated by GIMAP5

Nicholas Chadwick, Leo Zeef, Virginia Portillo, Joanna Boros, Sarah Hoyle, Jaap C.L. van Doesburg, Anne-Marie Buckle

Journal:

Blood Cells, Molecules, and Diseases

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

27

Bisphosphonates in GIO: Novel insights in their action

L. Moro, N. Bivi, M. Romanello, J.Z. Bereszczak, L.A. Zeef, D. Del Neri, F. Quadrifoglio, F.L. Brancia, G. Tell

Journal:

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

28

Sdf-1/Cxcr4 signalling regulates proliferation during cortical development

J. Pritchett, C. Wright, L. Zeef, B. Nadarajah

Journal:

International Journal of Developmental Neuroscience

Year:

2006

Language:

english

File:

PDF, 76 KB

english, 2006

29

Macrophage Migration Inhibitory Factor: A Central Regulator of Wound Healing

Matthew J. Hardman, Alexander Waite, Leo Zeef, Matthew Burow, Toshinori Nakayama, Gillian S. Ashcroft

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.82 MB

english, 2005

30

Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin

Daniel Mendoza-Villanueva, Leo Zeef, Paul Shore

Journal:

Breast Cancer Research

Year:

2011

Language:

english

File:

PDF, 858 KB

english, 2011

31

Identification of novel Notch target genes in T cell leukaemia

Nicholas Chadwick, Leo Zeef, Virginia Portillo, Carl Fennessy, Fiona Warrander, Sarah Hoyle, Anne-Marie Buckle

Journal:

Molecular Cancer

Year:

2009

Language:

english

File:

PDF, 2.45 MB

english, 2009

32

Genetic analysis of theTrichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation

Scott E Levison, Paul Fisher, Jenny Hankinson, Leo Zeef, Steve Eyre…

Journal:

Year:

2013

Language:

english

File:

PDF, 405 KB

english, 2013

33

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

Ben M Minogue, Stephen M Richardson, Leo AH Zeef…

Journal:

Arthritis Research & Therapy

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

34

P621 INTEGREN β1 REGULATES HEPATIC STELLATE CELL ACTIVATION VIA THE ACTIN MYOSIN CYTOSKELETON

Martin, K., Pritchett, J., Harvey, E., Athwal, V., Llewellyn, J., Streuli, C., Zeef, L., Hanley, N., Piper Hanley, K.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 67 KB

english, 2014

35

An experimental model for Huntington's chorea?

Zeef, Dagmar H., Jahanshahi, Ali, Vlamings, Rinske, Casaca-Carreira, João, Santegoeds, Remco G., Janssen, Marcus L.F., Oosterloo, Mayke, Temel, Yasin

Journal:

Behavioural Brain Research

Year:

2014

Language:

english

File:

PDF, 900 KB

english, 2014

36

Changes in brainstem serotonergic and dopaminergic cell populations in experimental and clinical Huntington’s disease

Jahanshahi, A., Vlamings, R., van Roon-Mom, W.M.C., Faull, R.L.M., Waldvogel, H.J., Janssen, M.L.F., Yakkioui, Y., Zeef, D.H., Kocabicak, E., Steinbusch, H.W.M., Temel, Y.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.82 MB

english, 2013

37

A novel cathepsin from the mussel (Perna perna) (Linne)

Zeef, L.A.H., Dennison, C.

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1988

Language:

english

File:

PDF, 342 KB

english, 1988

38

S1739 Interleukin-23/TH17 Pathway Expression in Chronic Trichuris Muris Colitis: Lessons for Iatrogenic Helminthosis

Levison, Scott E., McLaughlin, John, Zeef, Leo, Pennnock, Joanne

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

39

Transcriptome and Proteome Analysis of Osteocytes Treated with Nitrogen-Containing Bisphosphonates

Bivi, Nicoletta, Bereszczak, Jessica Z., Romanello, Milena, Zeef, Leo A. H., Delneri, Daniela, Quadrifoglio, Franco, Moro, Luigi, Brancia, Francesco L., Tell, Gianluca

Journal:

Journal of Proteome Research

Year:

2009

Language:

english

File:

PDF, 3.25 MB

english, 2009

40

A Revised Bacterial Polypeptide Chain Elongation Cycle with a Stepwise Increase in Restriction of Unwanted Ternary Complexes by the Ribosome †

Bosch, Leendert, Vijgenboom, Erik, Zeef, Leo A. H.

Journal:

Year:

1996

Language:

english

File:

PDF, 154 KB

english, 1996

41

Characterization of Nutrient-Induced Dispersion in Pseudomonas aeruginosa PAO1 Biofilm

Sauer, K., Cullen, M. C., Rickard, A. H., Zeef, L. A. H., Davies, D. G., Gilbert, P.

Journal:

Journal of Bacteriology

Year:

2004

Language:

english

File:

PDF, 1.03 MB

english, 2004

42

The Effect of Type 1 IFN on Human Aortic Endothelial Cell Function In Vitro : Relevance to Systemic Lupus Erythematosus

Reynolds, John A., Ray, David W., Zeef, Leo A.H., O'Neill, Terence, Bruce, Ian N., Alexander, M. Yvonne

Journal:

Journal of Interferon & Cytokine Research

Year:

2014

Language:

english

File:

PDF, 510 KB

english, 2014

43

Basic science * 232. Certolizumab pegol prevents pro-inflammatory alterations in endothelial cell function

Heathfield, S., Parker, B., Zeef, L., Bruce, I., Alexander, Y., Collins, F., Stone, M., Wang, E., Williams, A. S., Wright, H. L., Thomas, H. B., Moots, R. J., Edwards, S. W., Bullock, C., Chapman, V.,

Journal:

Year:

2012

Language:

english

File:

PDF, 582 KB

english, 2012

44

The ETS Domain Transcription Factor Elk-1 Regulates the Expression of Its Partner Protein, SRF

Kasza, A., O'Donnell, A., Gascoigne, K., Zeef, L. A. H., Hayes, A., Sharrocks, A. D.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 782 KB

english, 2005

45

A Novel Immunomodulator, FTY-720 Reverses Existing Cardiac Hypertrophy and Fibrosis From Pressure Overload by Targeting NFAT (Nuclear Factor of Activated T-cells) Signaling and Periostin

Liu, W., Zi, M., Tsui, H., Chowdhury, S. K., Zeef, L., Meng, Q.-J., Travis, M., Prehar, S., Berry, A., Hanley, N. A., Neyses, L., Xiao, R.-P., Oceandy, D., Ke, Y., Solaro, R. J., Cartwright, E. J., Le

Journal:

Circulation Heart Failure

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

46

Ternary Complex Factor-Serum Response Factor Complex-Regulated Gene Activity Is Required for Cellular Proliferation and Inhibition of Apoptotic Cell Death

Vickers, E. R., Kasza, A., Kurnaz, I. A., Seifert, A., Zeef, L. A. H., O'Donnell, A., Hayes, A., Sharrocks, A. D.

Journal:

Molecular and Cellular Biology

Year:

2004

Language:

english

File:

PDF, 633 KB

english, 2004

47

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function

Vascotto, C., Bisetto, E., Li, M., Zeef, L. A. H., D'Ambrosio, C., Domenis, R., Comelli, M., Delneri, D., Scaloni, A., Altieri, F., Mavelli, I., Quadrifoglio, F., Kelley, M. R., Tell, G.

Journal:

Molecular Biology of the Cell

Year:

2011

Language:

english

File:

PDF, 2.12 MB

english, 2011

48

Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up-regulated

Castelli, L. M., Lui, J., Campbell, S. G., Rowe, W., Zeef, L. A. H., Holmes, L. E. A., Hoyle, N. P., Bone, J., Selley, J. N., Sims, P. F. G., Ashe, M. P.

Journal:

Molecular Biology of the Cell

Year:

2011

Language:

english

File:

PDF, 2.27 MB

english, 2011

49

Acceptance and Implementation of Information Policy

Zuurmond, A., Zeef, P., Gooren, W.

Journal:

International Review of Administrative Sciences

Year:

1992

Language:

english

File:

PDF, 1.80 MB

english, 1992

50

Gcn4 Is Required for the Response to Peroxide Stress in the Yeast Saccharomyces cerevisiae

Mascarenhas, C., Edwards-Ingram, L. C., Zeef, L., Shenton, D., Ashe, M. P., Grant, C. M.

Journal:

Molecular Biology of the Cell

Year:

2008

Language:

english

File:

PDF, 1.71 MB

english, 2008

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